Signs of pain in cats include trembling, meowing, restlessness, not being allowed to be touched, aggressive behavior, self-mutilation, loss of appetite, etc. These are all signs that cats are in pain. Once discovered, it is best to send the cat to the hospital as soon as possible. examine. Cats cannot speak, nor will they take the initiative to tell their owners where they are in pain. They can only show it through behavior, which requires the owner to observe carefully and pay more attention to the cat's condition.