Female cats can be neutered at 6-8 months old. Neutering before going into estrus is good for the female cat. If an adult female cat needs to be neutered after going into estrus, it is good for the female cat. Cats need to be vaccinated, in good spirits, and in good health before being sterilized. Cats must fast for 8 hours and water for 4 hours before sterilization. Breeders should clean the indoor environment to avoid residual food before taking the cat for sterilization. Bacteria cause postoperative infection in female cats.