Analysis of ingredients of Bayer anthelmintic drug for dogs "Bayer" anthelmintic drug in vivo

Bayer
Bayer contains three anthelmintic ingredients, febantel, pyrantel and praziquantel.
Non-Bantaire
Introduction:
It is a benzimidazole precursor anthelmintic and has been approved as an anthelmintic for various animals in the United States.
It is converted into fenbendazole (and its sulfoxide) and oxfendazole in the gastrointestinal tract and then exerts an effective anthelmintic effect.
Anthelmintic type:
Broad-spectrum internal anthelmintic, targeting nematodes, including various types of nematodes, roundworms, tapeworms, etc.
Represents anthelmintics:
Bayer’s Baichongqing
Points to note:
① It is used to deworm various animals. When used on cats and dogs, it is often combined with praziquantel to expand the scope of deworming;
② Not to be used during pregnancy as it may cause teratogenic effects on the fetus.
Pyrantel pamoate
Introduction:
Also known as anthelminin and pyrantel, it is a synthetic broad-spectrum and highly effective anthelmintic drug.
Principle of anthelmintic:
The function is to inhibit cholinesterase, causing the muscles of the insect body to contract strongly and cause spastic paralysis; but it does not cause turmoil in the roundworms. Roundworm, hookworm, pinworm and mixed infections, hookworm is the most effective.
Represents anthelmintics:
① Dog Xinbao: an anthelmintic drug in the body, mainly targeting the "roundworm" function
② Pagoda sugar: human roundworm anthelmintic, old drug, rarely used now
Notes:
① It is prohibited for patients with acute hepatitis, acute nephritis and severe heart disease.
② Use with caution in patients with coronary heart disease, a history of severe ulcers, or patients with fever.
③ It is contraindicated in patients with liver insufficiency.
Praziquantel
Introduction:
A broad-spectrum antiparasitic drug, an anthelmintic drug for humans and animals, and an essential drug by the World Health Organizationdrugs on the Model List of Drugs.
Pesticide type:
Used for the treatment and prevention of schistosomiasis, cysticercosis, paragonimiasis, hydatid disease, fasciolosis, echinococcosis, helminth infections, etc. p>
Represents anthelmintics:
Praziquantel tablets/Cedilil: anthelmintics for human use
Praziquantel tablets are also available for veterinary use
Notes:
① Mainly metabolized by liver
② It can enter breast milk, and the content is about 25% of the drug concentration in serum. After use during lactation, it will take 72 hours before breastfeeding again
③ Contraindicated in patients with liver, kidney, and heart dysfunction
Analysis
① Two of the three repellent ingredients are Used in human anthelmintics, indicating lower toxins
② The three repellent ingredients have not been directly used in agricultural pesticides, indicating that the toxins are low
③ The safety level is relatively high among the pet anthelmintics on the market. People with liver, kidney and heart dysfunction and pets who are pregnant and lactating should not use it.
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