Dogs will die after eating chlorpheniramine

As long as the drug contains acetaminophen and chlorpheniramine maleate, the toxicity and lethal dose to dogs is almost the same as isoniazid. Although isoniazid is harmless to humans, it has a very strong poisoning effect on dogs. If administered at 0.15/kg, dogs will die within 90 minutes.

What is isoniazid

Isoniazid was invented in 1952 and is currently the main anti-tuberculosis drug in humans. Isoniazid is highly selective against Mycobacterium tuberculosis and has almost no effect on other bacteria. It can be said to be the natural nemesis of Mycobacterium tuberculosis. Isoniazid is a good medicine for tuberculosis patients.
Isoniazid is a first-line anti-tuberculosis drug recommended by the World Health Organization (WHO) and is highly effective and cheap. It is a widely used drug, but as a prescription drug, it is not available for purchase and use.

Causes of fatality of isoniazid

At therapeutic doses, isoniazid is very toxic to humans, but it can be fatal to dogs if ingested. After isoniazid enters the dog's body, it usually reaches the peak plasma value in about 30 minutes, and the presence of the drug can be detected in the blood, cerebrospinal fluid, and tissue fluid of most organs. Isoniazid can cause myocardial necrosis in dogs and cause severe metabolic acidosis. If rescue is not carried out in time, the dog can easily die.